How to Find and Purchase Affordable Generic Drugs Using TrumpRx.gov
Learn how to use TrumpRx.gov with Amazon, GoodRx, and Cost Plus to find low-cost generic drugs. Step-by-step guide with tips.
Introduction
In a major push to lower prescription costs, the White House recently expanded its TrumpRx discount platform by adding over 600 generic drugs. This expansion came through partnerships with Amazon Pharmacy, GoodRx, and entrepreneur Mark Cuban’s Cost Plus Drug Company. Now, when you visit TrumpRx.gov, you can compare prices across these participating pharmacies and find the lowest possible cost for your medications. This guide walks you through the entire process—from checking what you need to successfully purchasing your generics at a fraction of the usual price.

Note: TrumpRx is designed for U.S. residents with a valid prescription. Always consult your healthcare provider before making any changes to your medication regimen.
What You Need
- A valid prescription from a licensed healthcare provider
- Internet access and a device (computer, tablet, or smartphone)
- Personal information (name, address, payment method) for purchases
- Optional: Insurance card or discount card if you want to apply additional savings
- Optional: A list of your current medications and dosages for quick searches
If you already use Amazon Pharmacy, GoodRx, or Cost Plus Drug Company, your existing account credentials may work on TrumpRx.gov. If not, you can create new accounts during the checkout process.
Step-by-Step Guide
Step 1: Visit TrumpRx.gov
Open your web browser and go to TrumpRx.gov. The homepage will present a search bar prominently displayed. You’ll also see logos of partner services: Amazon Pharmacy, GoodRx, and Cost Plus Drug Company. No login is required to start browsing prices.
Tip: Bookmark the site for quick access later.
Step 2: Search for Your Generic Drug
Enter the name of the medication in the search bar. For this exercise, you should only look for generic versions, as TrumpRx’s new addition focuses on over 600 generics from the partners. Use the generic name (e.g., metformin instead of Glucophage) for best results. If you’re unsure of the generic equivalent, ask your doctor or pharmacist.
After you click Search, the site will display a list of available options—sometimes multiple strengths and forms (tablets, capsules, etc.). Select the one matching your prescription.
Step 3: Compare Prices Across Partners
Once you select a specific drug, TrumpRx will show a comparison table with prices from Amazon Pharmacy, GoodRx, and Cost Plus Drug Company (Mark Cuban’s company). Each row lists:
- Pharmacy partner name
- Price for a standard supply (usually 30 or 90 days)
- Any membership or shipping requirements
- Estimated total cost including shipping
Important: The lowest price may vary depending on your location, insurance status, and whether you use a discount coupon. GoodRx, for example, offers coupons that can be used at local pharmacies, while Amazon Pharmacy and Cost Plus are primarily online mail-order services.
Take your time to review each option. The White House states that TrumpRx provides “one source to ensure that you’re getting the lowest possible cost,” but it’s still wise to double-check with your own insurance plan for any additional savings.
Step 4: Choose a Pharmacy and Start Checkout
Click the Select button next to your preferred partner. This will redirect you to that partner’s website (Amazon Pharmacy, GoodRx, or Cost Plus) to complete the purchase. For example:
- Amazon Pharmacy: You’ll log into your Amazon account (or create one) and proceed to checkout. Prime members may get free shipping, but non-Prime users can still buy with a shipping fee.
- GoodRx: You’ll see a coupon code or a link to print a card. You can use GoodRx at thousands of local pharmacies (like CVS, Walgreens) or through GoodRx’s own mail-order service.
- Cost Plus Drug Company: You’ll go to their website, create an account, and order directly. They offer transparent pricing (15% markup on wholesale cost plus a $3 pharmacy fee).
No matter which partner you choose, make sure you have your prescription ready. Some partners may require you to upload a copy or provide your doctor’s contact information.

Step 5: Complete the Purchase
Follow the checkout process of the chosen partner. You’ll typically need to:
- Provide personal and shipping details
- Enter payment information
- Apply any discount codes or insurance if desired (optional)
- Review the final price before confirming
If you’re using GoodRx, note that you can either buy directly online or take the coupon to a local pharmacy. For local pickup, you’ll present the coupon at the pharmacy counter along with your prescription.
Once the order is placed, you’ll receive a confirmation email. For online orders, the medication will be shipped to your address within a few days (standard shipping times vary by partner).
Step 6: Receive Your Medication and Verify the Details
When your package arrives (or you pick it up), check the label to confirm the drug name, strength, and dosage instructions match your prescription. Also compare the price you actually paid with the price shown on TrumpRx—this ensures there were no hidden fees.
If anything seems off, contact the partner’s customer service immediately. Keep the receipt for your records, especially if you plan to submit a reimbursement claim to your insurance.
Tips for Maximizing Savings
- Compare regularly: Drug prices change frequently. Check TrumpRx.gov every month or two to see if a different partner offers a better deal on your medication.
- Ask about 90-day supplies: Many generics are cheaper when bought in larger quantities. Some partners offer bulk discounts.
- Check for manufacturer coupons: Even though you’re using a discount platform, the drug manufacturer may have its own savings program. Combine them if allowed.
- Talk to your doctor: If a generic is still expensive, ask if a cheaper alternative (therapeutic substitution) is appropriate.
- Use your insurance first: For some drugs, your insurance copay may be lower than the cash price on TrumpRx. Always compare.
- Monitor your bank statements: Ensure that the charge matches the amount you agreed to. Set up payment alerts to avoid unexpected debits.
- Be aware of membership requirements: Amazon Pharmacy may require a Prime membership for free shipping; GoodRx Gold (a paid subscription) unlocks even deeper discounts. Factor those costs into your comparison.
- Read the fine print: Some sellers may have restrictions on certain medications (controlled substances, temperature-sensitive drugs). Always verify before ordering.
With the White House’s expansion of TrumpRx combined with the power of Amazon, GoodRx, and Mark Cuban’s Cost Plus, you now have unprecedented access to affordable generics. By following this guide, you can confidently navigate the platform and keep your prescription costs low.